Clinical Advisory

Skincare can feel overwhelming—you're constantly being pulled in different directions, told what to use, what to avoid, and who to listen to. But let us be clear: you are already beautiful, just as you are.

At PowerV™, we see you. We hear your frustration. And we’re here not to fix you—but to support you. Skincare shouldn't make you feel less than. It should feel like a return to yourself. Our mission is to meet you where you are and walk alongside you with intention, compassion, and science.

PowerV™ is NOT recommended for individuals who are currently undergoing or planning active fat-reduction treatments such as Kybella®, radiofrequency, or ultrasound-based facial contouring. If your goal is to continue reducing volume, using PowerV™ during this time may not align with your intended results.

However, if you are UNHAPPY with the outcome of a fat-reduction procedure and wish to support your remaining facial structure and volume, PowerV™ may be appropriate. It’s designed to maintain the skin’s natural environment and appearance - help preserve visual harmony and resilience over time.

Additionally, avoid using PowerV™ if you have a known sensitivity to any of its ingredients.

Honestly... I think I was just really overwhelmed.

There were so many options out there—so many routines, so many promises—but nothing was actually delivering what I was looking for.

I wasn’t chasing a miracle product.

What I wanted was something that could genuinely support the skin long-term—from the inside out. Something that didn’t just sit on the surface, but actually worked from the cellular level, helping with things like fat cell preservation, nucleus health, DNA protection… the things that really matter as we age.

And I couldn’t find that.

So I decided to create it.

I wasn’t trying to outdo anyone. I just wanted to build something that was honest, effective, and rooted in science—not marketing.
This isn’t just a serum. It’s skincare that supports your skin on every level:
fat cell activity with patented plant stem cells, so you don’t experience that hollow, gaunt look as you age.
oxidative stress with one of the strongest antioxidants on Earth—which means fewer fine lines and stronger skin over time.
triple-barrier hydration system to keep your skin deeply moisturized, calm, and resilient.
natural collagen and elastin production by caring for your skin’s nucleus—where it all begins.

But beyond the science, there’s something else that really pushed me to create this.
So much skincare today comes at a cost.

Harsh actives, mystery reactions, hormone-disrupting ingredients…

And when people turn to “medical-grade” options, no one talks about the other side effects—like fat loss, long-term skin thinning, and even damage to the skin barrier.

It’s heartbreaking, honestly.

Because women are constantly being sold quick fixes and empty promises, usually by preying on their insecurities. And that’s exactly what we’re against.

At PowerV, we’re mindful of all of it.

We don’t believe in fear marketing. We believe in transparency. And in giving your skin exactly what it needs—not just now, but for the long term.

And I hope that helps women out there make better, more informed choices—without having to spend thousands on treatments that don’t always have your health in mind.

Because with consistent use, PowerV truly gives your skin what it needs to stay full, resilient, and beautiful—naturally.

PowerV™ is one of the only topical products that includes PhytoCellTec™ Argan, a patented stem cell active clinically shown to support both dermal and hypodermal stem cells—including the stem cells responsible for maintaining your skin’s natural fat cushion.

As we age, the hypodermal stem cells that replenish facial fat cells become less active, leading to volume loss, sagging, and deeper folds. PhytoCellTec™ Argan has been shown to:

• Boost hypodermal stem cell proliferation by 147% to 171% (in vitro)
• Support visible firmness and fullness in the nasolabial area
• Help preserve the skin’s deep structural integrity over time

This is important because facial fat isn’t just about fullness—it provides the support, lift, and softness that define a youthful look.

By maintaining the vitality of these deep skin cells, PowerV™ may help delay the visible signs of structural loss that often lead people to seek injectable fillers. It’s not a replacement for filler, but it is one of the only clean, science-backed ways to help support volume naturally—before you feel the need for more invasive options.

We couldn’t find a formula that supported anti-aging from every angle and still respected the skin—so we built it ourselves. PowerV supports anti-aging from all angles—hydration, firmness, antioxidant protection, and barrier repair—using clinically backed ingredients in one formula. No trends, no toxicity—just deep skin science.

Most skincare focuses only on the surface—hydrating, exfoliating, or temporarily plumping. PowerV™ goes deeper.

PowerV™ is one of the only topical products that includes PhytoCellTec™ Argan, a patented stem cell active clinically shown to support both dermal and hypodermal stem cells—including the stem cells responsible for maintaining your skin’s natural fat cushion.

As we age, the hypodermal stem cells that replenish facial fat cells become less active, leading to volume loss, sagging, and deeper folds.

Because as you age, the stem cells that maintain collagen, elastin, and even fat cushion regeneration begin to slow down—leading to fine lines, sagging, and deep folds.

Clinically Proven Results Include

171% increase in hypodermal stem cell proliferation (in vitro)

13.1% reduction in nasolabial fold depth in 12 weeks

26.2% wrinkle reduction in crow’s feet area

12.7% increase in overall skin density

90% increase in dermal stem cell vitality (via sphere formation)

Boosted Sox2 gene expression, a marker of regenerative potential

This is important because facial fat isn’t just about fullness—it provides the support, lift, and softness that define a youthful look.

By maintaining the vitality of these deep skin cells, PowerV™ may help delay the visible signs of structural loss that often lead people to seek injectable fillers. It’s not a replacement for filler, but it is one of the only clean, science-backed ways to help support volume naturally—before you feel the need for more invasive options.

By reinforcing both dermal and hypodermal layers, PowerV™ helps visibly delay signs of aging at the structural level—before you feel the need for filler.

But it doesn’t stop there.

PowerV™ also includes the world’s most powerful antioxidant: Astaxanthin—clinically shown to reduce oxidative stress, one of the core drivers of skin aging. It helps visibly:Your Barrier Has Backup, Too.

With Beta-Glucan, Ceramide Complex, and Squalane, PowerV™ strengthens the outer barrier and restores moisture balance—helping your skin stay calm, hydrated, and resilient. Why? Because when your barrier is compromised, inflammation rises—and aging speeds up.

PowerV™ Tackles Aging From All Angles

This isn’t just skincare. It’s a structural strategy—designed to work with your biology, not against it.

Fat layer preservation

volume support

Collagen + elastin stem cell support

Antioxidant defense against daily skin stress

Barrier + hydration for sensitive skin.

This isn’t just skincare. It’s a structural strategy—designed to work with your biology, not against it.

Skincare is powerful—but it’s only one part of the equation.

At PowerV, we believe in supporting your skin from all angles: topically with intelligent, science-backed ingredients, and internally through the choices you make every day. If you're investing in skincare, it only makes sense to support it with healthy habits that reinforce those results—not work against them.

That means prioritizing anti-inflammatory foods, berries and fruits rich in antioxidants, lean proteins to support collagen, and regular movement to improve circulation and cellular repair. Because let’s be honest—if you’re spending on advanced skincare, but eating in ways that cause inflammation and stress, you’re undoing the very results you're trying to achieve.

Healthier eating habits and regular exercise are just as important as what you apply on your face. When combined with PowerV, you’re not just caring for your skin—you’re supporting your body, your mind, and your long-term well-being.

Yes. No endocrine disruptors, no parabens, no synthetic fragrance. Every ingredient is safe, effective, and chosen with purpose.

Astaxanthin, one of the most powerful antioxidants, with 6,000 times the oxidative stress-fighting strength of Vitamin C (*). It's known for its ability to help protect the skin from environmental stressors and visible signs of aging.

Beta-Glucan is a powerful ingredient known for its ability to deeply hydrate and support the skin barrier. It helps calm and repair sensitive skin, providing long-lasting moisture retention. While Hyaluronic Acid is also a great hydrator, Beta-Glucan offers enhanced soothing and barrier-strengthening benefits, making it ideal for skin that is prone to irritation or sensitivity.

Yes—patented, biotech-developed plant stem cells, not just plant extracts. They're studied for improving firmness and skin density over time.

Yes. It’s made to support skin health without irritation—thanks to barrier-strengthening ingredients like ceramides, squalane, and beta-glucan.

Many users notice improvements with continued use. Clinical studies on our core ingredients show that with consistent use, skin elasticity, hydration, and firmness typically improve within 4-8 weeks.

As we age, the supportive fat layer beneath the skin naturally begins to thin—leading to visible sagging, hollowness, and a loss of firmness over time. PowerV is formulated to support the skin barrier, boost hydration, and strengthen elasticity, which helps maintain the look of plump, resilient skin.

By nourishing the skin’s foundation and reinforcing its structure with ingredients like Beta-Glucan, Ceramides, and Squalane, PowerV helps preserve the healthy environment surrounding these fat cells—supporting long-term skin volume and bounce.

That’s why we advocate for prevention, not just correction. Supporting your skin early helps protect its structure, slow visible signs of aging, and keep your skin strong, balanced, and radiant over time.

Imagine your skin is a busy city, and your cells are the workers. Now picture a storm of free radicals (unstable molecules caused by sun, pollution, and stress) constantly trying to damage the buildings (your collagen and elastin).

Astaxanthin acts like a microscopic bodyguard — standing between the chaos and your collagen. It neutralizes those free radicals before they can break things down, helping prevent wrinkling, dullness, and sagging.

Under the microscope: Astaxanthin is absorbed into the lipid layer of your skin cells, where it sits at the membrane and protects cell structures from oxidative stress. This keeps skin cells functioning longer and prevents inflammation that leads to aging.

Beta-Glucan (Moisture Magnet + Cell Communicator)

Inside the deeper layers of your skin, there are cells that regulate repair, hydration, and immunity. These cells communicate like neighbors—but when your skin is stressed, the lines get fuzzy.

Beta-Glucan works like a messenger and water reservoir. It attaches to receptors on immune cells and helps regulate inflammation, while simultaneously pulling moisture deep into the skin.

Microscopically: Beta-Glucan molecules penetrate the epidermis and form a gel-like matrix between skin cells, trapping water while signaling cells to reduce inflammation and improve repair. This leads to smoother, healthier skin from within.

They are Your Lipid Wall Builders.
Your skin barrier is made of lipids (fats) that form a protective wall—like the bricks and mortar of a building. With age, that wall gets cracks (dryness, irritation, sensitivity).

Ceramides fill in the “mortar,” while Squalane acts like a flexible, skin-identical oil that seals it all together—without clogging pores.

Microscopically: These lipids physically integrate into the outermost layer of skin cells (stratum corneum), strengthening the skin’s structure and preventing water loss. A healthy barrier also reduces exposure to pollution and bacteria, which can accelerate aging.

Patented Plant Stem Cells - The Cellular Architects. Inside your skin’s “construction zone” (especially at the dermal-epidermal junction, where firmness and elasticity are regulated), signals start to slow with age. That means less collagen, less regeneration, more visible aging.

PowerV’s plant stem cells are engineered to mimic the cell-signaling functions of young, healthy skin. They don’t turn into new skin cells—but they can stimulate the surrounding cells to act younger and regenerate better.

Under the microscope: These stem cell actives release bio-signals (called growth factors) that help boost fibroblast activity, encouraging the production of collagen and elastin fibers, which support firmness and volume.

Beneath the skin is a thin layer of fat (adipose tissue). With age, this layer thins out—leading to hollowing, sagging, and a loss of bounce.

While topical skincare generally don't replace fat, ingredients like Beta-Glucan, Ceramides, and antioxidants help preserve the environment around fat cells—keeping them healthier, hydrated, and less inflamed.

In your skin: When the tissue around fat cells is nourished and inflammation is reduced, volume is better preserved. The skin stays visibly fuller, more lifted, and youthful-looking for longer."

Yes—facial fat volume plays a major role in how youthful, lifted, and resilient your skin appears. As we age, the fat cushion beneath the skin naturally thins due to a decline in stem cell activity, structural breakdown, and certain aesthetic treatments. Supporting the skin’s ability to maintain its natural fat-supportive environment can help preserve facial harmony, reduce visible hollowing, and delay the need for more invasive interventions like fillers. PowerV™ is uniquely formulated to nourish this environment, offering subtle support for long-term volume and skin structure.

Yes—in your body (abdomen, thighs, etc.), fat cell count stays mostly stable. They shrink or expand based on weight.
BUT… your facial skin has a small, local pool of stem cells in the hypodermis designed to replace lost fat cells gradually—and that process slows with age.

NO—these are two very different biological processes.

When you lose weight intentionally (through diet and exercise), your body burns stored fat for energy. The fat cells shrink in size, but their total number stays the same—this is a healthy, systemic process.

Facial volume loss, on the other hand, is often driven by localized cell depletion, especially in the skin's hypodermis. This can happen due to aging (when stem cell activity declines), or after certain aesthetic procedures (when trauma disrupts the fat-supportive environment). In these cases, you’re not just shrinking fat—you’re losing the cells themselves, along with their ability to regenerate.

So while weight loss affects fat distribution in the body, facial volume loss is about structural decline—a completely different issue that requires regenerative skin support, not fat burning.

You can be a healthy weight and still experience hollowing in the cheeks or under-eyes due to the natural decline in regenerative fat cells in the skin.

Unlike healthy weight loss—where fat cells shrink but the overall number remains stable—age-related volume loss involves an actual reduction in the number and vitality of fat cells in the face.

On the other hand, If you're planning to lose weight, it's important to do so with a gradual, well-supported plan that gives your skin time to adapt. Rapid weight loss can leave the skin without the fat cushion it needs to appear full, smooth, and lifted—especially in the face. Slower, more balanced weight loss allows skin to tighten and recover while maintaining its structural integrity.

PowerV™ is formulated to support that specific regenerative mechanism—not by shrinking fat cells systemically, as occurs in weight loss—but by supporting the visible integrity of skin structure through the natural, age-regulated activity of hypodermal stem cells. This process helps maintain the skin’s natural volume and resilience in areas where regenerative fat support is needed.

In your deepest skin layer (called the hypodermis), your body stores adipose-derived stem cells (ADSCs). These special cells:

• Help maintain your facial fat cushion
• Contribute to volume, bounce, and youthful appearance
• Naturally decline in both number and vitality as you age

Yes. Stem cells are like blank slates. Under the right signals, they can become:

• Fibroblasts (collagen-producing)
• Keratinocytes (for skin surface renewal)
• Adipocytes (fat cells) that help maintain facial volume

This is a natural, subtle process regulated by your body. It doesn’t happen unless the skin needs to replenish lost fat.

PowerV™ features PhytoCellTec™ Argan, a patented stem cell technology that:

• Supports the vitality of aged hypodermal stem cells
• Helps preserve the skin’s ability to maintain its fat-supportive structure over time

True for body fat, but in face & OR skin, stem cells can become fat cells when needed to maintain volume.

False. Your body controls what converts, when, and how much. PowerV™ supports this process without overriding natural regulation.

PowerV™ is not a substitute for injectable fillers, but it may help extend the time before you feel the need for them. Fillers work by instantly replacing lost volume beneath the skin. PowerV™, on the other hand, supports the skin's natural structure over time by helping maintain the environment that protects fat cell vitality and skin resilience.

By supporting the skin’s regenerative microenvironment—particularly in the hypodermis—PowerV™ may help your face maintain a more lifted, balanced appearance as you age. For clients looking for a non-invasive way to support long-term volume and delay early signs of structural loss, PowerV™ offers a gentle, science-backed approach.

NO - PowerV™ is not recommended for use during or after facial fat-reducing treatments, especially if your goal is to continue reducing facial volume.

However, if you're unhappy with the amount of volume lost—or you're looking to support the remaining structure of your skin—PowerV™ may be a supportive option. It’s designed to maintain the skin’s structural environment and resilience, to help preserve visible harmony over time.