PowerV
The New SkinCare by PowerV | Foundational Anti-Aging Anti-Oxidant Hydrating Barrier Serum with Patented Plant Stem Cells.
The New SkinCare by PowerV | Foundational Anti-Aging Anti-Oxidant Hydrating Barrier Serum with Patented Plant Stem Cells.
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Full INCI Ingredient List
Full INCI Ingredient List
Ingredients: Purified Water, Beta-Glucan (liquid), Glycerin Vegetable, Propanediol (ZEMEA), PhytoCellTecTM Argan, MossCellTecTM No.1, Ceramide Complex (Liquid), FSS Astaxanthin Extract SF, Neossance Hemisqualane, NeoDefend, Xanthan Gum Clear (Powder), DL-Panthenol (Pro-Vitamin B5) Powder, Organic Sunflower Lecithin Liquid
Important - If you are currently undergoing, or have recently undergone, a facial fat-reduction treatment please consult our Clinical Advisory Page before using PowerV™.
Available Now | Dermatology Tested on Sensitive Skin | Foundational Anti-Aging Anti-Oxidant Hydrating Barrier Serum with Patented Plant Stem Cells.
Clinically proven to reduce wrinkles backed by Swiss biotech lab Mibelle Biochemistry
PowerV™ uses patented actives clinically studied for volume support in deeper skin layers.
Unlike most serums that focus only on surface appearance, PowerV™ includes PhytoCellTec™ Argan, shown in clinical studies to support visible firmness and improve density in the dermal–hypodermal junction, a key area where skin often begins to lose volume with age.
It also features MossCellTec™ No. 1, a 4 times award-winning ingredient recognized globally for innovation in stress adaptation, skin resilience and barrier support. Clinically studied to help skin adapt to stress and environmental changes, it reinforces the barrier and supports a smoother, more even-toned complexion.
Together, these patented stem cell technologies offer a layered approach to skin health, supporting visible volume, hydration, tone, and resilience over time.
In addition to its patented stem cell technology, PowerV™ is formulated with a proprietary blend of potent antioxidant (ASTAXANTHIN) and barrier-supportive ingredients selected for their ability to calm, protect, and visibly strengthen skin over time. These ingredients help defend against oxidative stress one of the biggest contributors to premature aging while also addressing dehydration and surface-level irritation. The result is a smoother, more resilient complexion that supports your skin’s long-term health. Every component was chosen to work in harmony with sensitive skin and aging concerns, offering visible results without harsh actives or ingredient overload.
Clinically proven to reduce wrinkles, backed by Swiss biotech lab Mibelle Biochemistry. Ingredient Level. PowerV uses the same concentration used in clinical trials.
Week 2–4: Surface Barrier & Hydration Support
Key Ingredient: MossCellTec™ No. 1 (twice daily)
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Up to 17.5% increase in skin hydration
→ Skin appears more supple and dewy, especially in dry or changing climates. -
Up to 20% reduction in transepidermal water loss (TEWL)
→ Helps support the skin’s ability to retain moisture, reducing the appearance of dryness or flaking. -
Up to 15% reduction in overall wrinkle depth
→ Fine lines on the forehead and around the mouth looked visibly improved. -
91% of participants showed improvement in skin barrier function
→ Skin looked calmer, more even-toned, and less reactive to environmental changes. -
Visible improvement in tone homogeneity and skin texture
→ Complexion appeared smoother, with fewer uneven patches or areas of blotchiness.
Week 6–8: Skin Firmness, Density & Wrinkle Depth
Key Ingredient: PhytoCellTec™ Argan (twice daily)
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Up to 12.7% increase in skin density (measured via ultrasound)
→ Skin appeared visibly firmer and more supported, helping reduce the look of skin thinning. -
Up to 26.2% reduction in crow’s feet wrinkle depth
→ The eye area appeared softer and smoother with improved texture in motion and at rest. -
11% improvement at the dermis–hypodermis junction (thigh study)
→ Supports firmer-looking skin in deeper layers often associated with early signs of visible volume change.
Week 12: Visible Volume Support & Contour Softening
Key Ingredient: PhytoCellTec™ Argan (half-face study)
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13.1% reduction in nasolabial fold depth
→ Smile lines appeared less deep and more refined, contributing to smoother mid-face contours. -
Clinically observed improvement in mid-face smoothness.
→ Participants noted enhanced softness and visibly smoother appearance in areas commonly prone to expression lines and early signs of volume change / loss.
Disclaimer The above results are drawn from ingredient-specific clinical studies using MossCellTec™ No. 1 and PhytoCellTec™ Argan in controlled applications. These percentages reflect outcomes observed in either half-face, full-face, or forearm studies. PowerV™ combines both patented stem cell actives at clinically suggested levels, along with additional antioxidant and barrier-supportive ingredients.
While we expect comparable benefits based on ingredient performance, individual results may vary, and final outcomes depend on multiple factors including skin type, consistency of use, and environment. This information does not constitute medical advice or claim to treat, cure, or prevent any skin condition.
The Future of Skincare Starts with Protecting Your Skin Barrier
Your skin barrier is the foundation of youthful, resilient skin, a natural shield that locks in hydration, defends against pollutants, and helps keep your skin looking healthy and firm. But most people are unknowingly disrupting their skin barrier every day with harsh exfoliants, synthetic irritants, and moisture-stripping products.
How a Weakened Skin Barrier Can Contribute to Visible Aging:
Increased Water Loss → Dehydration can make fine lines appear more pronounced.
Weakened Defense Against UV & Pollutants → Daily exposure can impact skin firmness and accelerate visible signs of aging.
Chronic Irritation & Sensitivity → Skin may become less resilient and slower to recover.
Disrupted Microbiome → Harsh skincare can throw off skin’s natural balance, leading to long-term visible stress.
Many skincare products promise quick results but often create a cycle of overuse, irritation, and premature signs of aging. Instead of supporting skin health, they can leave the barrier compromised.
The New SkinCare by PowerV | Dermatology Tested on Sensitive Skin - Supports Long Term Skin Health & Visible Sings of Aging.
Unlike conventional skincare that strips and over-exfoliates, The New SkinCare is designed to restore balance, strengthen your skin barrier, and help future-proof your skin. It is dermatology tested on sensitive skin making it an ideal choice as a non-irritating advanced biotech anti-aging serum.
Supports Skin Barrier Strength → Ceramides, Squalane, and Beta-Glucan help replenish the skin’s natural lipids, supporting moisture retention and barrier resilience.
Defending Against Oxidative Stress → Astaxanthin, one of the most potent antioxidants studied, offers antioxidant potential up to 6,000 times greater than Vitamin C in singlet oxygen neutralization.*
Why Antioxidants Are Essential for Visible Skin Aging
Every day, your skin is exposed to UV radiation, pollution, and blue light, factors that contribute to oxidative stress, a major driver of collagen breakdown, visible loss of elasticity, and premature wrinkles.
Astaxanthin vs. Other Antioxidants: Unlike Vitamin C and other water-soluble antioxidants, Astaxanthin is lipid-soluble, meaning it can absorb into skin’s lipid layers and help neutralize free radicals before they cause visible damage.
Photoprotective Benefits: Studies suggest Astaxanthin may help reduce the appearance of sun damage, supporting more even skin tone and long-term skin wellness.
Longer-Lasting Protection: While many antioxidants degrade quickly when exposed to light and oxygen, Astaxanthin remains stable, providing sustained protection against oxidative stress.*
Reference: NCBI Study on Astaxanthin & Wrinkle Reduction
Advanced Hydration & Barrier Support with Beta-Glucan
While Hyaluronic Acid (HA) hydrates the skin’s surface, Beta-Glucan penetrates more deeply, supporting barrier function and long-term moisture retention. Studies suggest Beta-Glucan can hold more moisture than HA* and may also support visible firmness, hydration, and skin comfort over time.
Reference: Maysama Study on Beta-Glucan vs. Hyaluronic Acid
Harnesses Plant Stem Cell Technology
PowerV™ features PhytoCellTec™ Argan, a patented ingredient clinically shown to revitalize both dermal and hypodermal stem cells IN VITRO, making it one of the only topical actives proven to support visible volume support.
- 147% to 171% increase in hypodermal stem cell proliferation(VITRO)
- 13.1% wrinkle depth reduction in the nasolabial fold after 84 days.(VIVO)
- 26.2% wrinkle reduction in the crow’s feet area.(VIVO)
- 12.7% increase in skin density in just 8 weeks.(VIVO)
Strengthening Skin Resilience & Stress Adaptation | Skin Health
PowerV™ includes MossCellTec™ No. 1, a patented active inspired by resilient moss plants that thrive in extreme environments. This next-generation ingredient has shown to support cell nucleus health in VITRO, skin adaptability, and barrier strength, especially in skin exposed to stress, aging, and harsh environments.
Clinically Measured Benefits:
- 15% wrinkle depth Reduction. (VIVO)
- Up tpo17.5% skin hydration (improved in 100% of participants). (VIVO)
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Up to 20% reduction in trans epidermal water loss (TEWL). (VIVO)
Sign of improved barrier function in 91% of participants. (VIVO) -
Visible improvement in skin tone uniformity. (VIVO)
Reduced redness and color variation, with noticeably smoother appearance
PowerV™ uses this clinical-grade moss cell technology to promote visible resilience, stress adaptation, especially after stress, travel, or procedures.
We don’t use basic plant extracts. Our stem cell actives are:
- Lab-grown from a rare Moroccan Argan tree, known for its extreme drought resistance.
- Deeper & targeted delivery and ingredient stability.
- Developed through sustainable biotechnology that protects rare plants while maximizing bioavailability.
PowerV™ also includes:
Beta-Glucan for Soothing & Barrier Support → A multi-functional ingredient known for its ability to hydrate, calm irritation, reduce oxidative stress, and support barrier, making it ideal for sensitive skin.
Clean, Vegan, non-Irrtation, Formulated with Non-Comedogenic Ingredients, and Respectful:
PowerV™ is vegan, essential oil-free, fragrance-free, and formulated without hormone-interfering, barrier-disrupting, or pore-clogging ingredients. This is clean beauty designed to support, not stress, your skin.
Reference: PubMed Study on Beta-Glucan & Skin Barrier Recovery
Why The New SkinCare by PowerV Is Designed for Skin Longevity.
Unlike conventional skincare that over-exfoliates, dehydrates, and weakens the skin barrier, The New SkinCare is formulated to:
- Reinforce the skin’s natural defense system.
- Deeply hydrate beyond the surface for long-lasting moisture
- Help protect against oxidative stress and visible signs of aging
- Support long-term skin health using advanced biotechnology
Your skin barrier isn’t just about looking good today, it’s about helping your skin stay resilient for decades to come.
Science-Driven. Biotech First. Skin Barrier-Focused. The Future of Skincare. The New way to Agre Gracefully. Preserve. Protect. Prevent. Ships Early October.
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PowerV is a new brand on the market, and I am often suspicious of new brands with premium pricing despite the fact they don't have the reputation to support it. I do have a background in money laundering and fraud investigations, however, and I like to do research on the brands I order from to determine if they're a fly-by-night situation trying to make a quick buck on people who don't know any better or if they really are trying to become an established and respected brand.As far as I can tell, PowerV is the latter. The marketing info on their website is impressive, and I appreciate that the founder is identified and associates herself with the brand on her LinkedIn, as well. I've seen new products with premium pricing with embarrassingly sparse websites and founders who don't appear to want to be associated with their products. PowerV gives a totally different impression, it appears that the founder cares deeply about her business and products. The science behind them according to their website seems compelling, but I'm not a scientist of any kind, nor am I really an expert in skincare ingredients, but it does look like there is actual effort being put in to become a recognized and trusted brand, which I appreciate.I was a little bummed about the packaging; the bottle that this serum comes in feels like cheap plastic, but the pump works well. I just expect high end packaging when I order products that have a high end price. I think of reputable brands like Omorovicza-- I have a similarly priced facial mist from them that has a heavy glass bottle, a pump that mists beautifully, and the thickest plastic cap I've ever seen. I don't love that the PowerV bottle is plastic because I'm paranoid about microplastics since learning the average adult has about 6g of them in their brain, which is enough to make a plastic spoon. Look it up, you're welcome. The founder's bio on their website also indicates that she tries to avoid endocrine disruptors in her products, and again, I'm not a scientist, but I'm pretty sure microplastics can be endocrine disruptors, so it would be nice to see this in a glass bottle in the future.That being said, my skin drank up the serum quickly and felt soft and velvety immediately after use. These are my very early first impressions of the product. It can take time and continued use to see real effects from almost any skincare product, but I didn't experience any irritation or negative effects, and I'll reiterate that I'm impressed with the claims of the science behind the ingredients touted on PowerV's website, even if I'm not impressed with how they were actually presented.I would cautiously recommend this serum after my first use, and I will continue incorporating it in my routine to see if there's any notable changes. I use and test a lot of skincare products, though, so it's difficult to attribute results to any one product or ingredient.I look forward to seeing how PowerV grows from here and I would happily test more of their products in the future based on my initial impressions.
I looked up the ingredient list for the serum and it looked promising. With three ceramides, plus Phytosphingosine, shows focus on moisture building and skin resilience. Gluconolactone is also present for mild exfoliation.There isn't any tamper evident seals on the box but there is a strong one over the bottle itself. The best by date is located on the bottom of the bottle and its about 2 years out.The pump action is smooth and I find one good press is enough product for my whole face. It spreads easily and absorbs fast. I use this both morning and evening, followed by sunscreen during the day. I can feel the hydrating effects very quickly. I haven't used it long enough to report on the long term effects yet so no comment there.
Reviewing skin care products can be tricky. Receiving the full benefit of the product can take weeks, if not months. This review is based on my initial impressions.This is pricey, but everyone has different budgets for skin care, and I’ve spent this much, and even more for a single product in the past. If the price is not a concern, then keep reading!The packaging is not my favorite. I found the gold on black on the box to be hard to read. The box also seemed to have been printed and folded wrong. The raw edge of the box was visible from the front. In my opinion, this should have been printed and folded so that the raw edge faced the back. The plastic container felt like something that any company could produce. HOWEVER, if the product inside of it is exceptional, then the packaging is no longer a consideration for me. I believe that may be the case with this item.The company included a variety of promotional graphics describing the benefits of using plant stem cells. I also looked at the website, which has a TON of information. Everything from the science behind the product to clinical research. This is described as a structural strategy that focuses on everything from preserving the skin barrier to providing antioxidant defense against the environmental factors that stress our skin to supporting the skin on a cellular level. This skin care isn’t just surface deep. This is meant to nourish the skin at a whole other level…a cellular level.In terms of ingredients, the company has used the combination of clean ingredients to support the skin…astaxanthin, beta-glucon, ceramides, squalane, and environmental adaptogens. Check out the website because it contains information about the benefits of each of these.The product itself is odorless. It’s slightly thicker than a serum, but not as thick as a lotion. It has a slippery feel and it glides easily onto the skin. I was worried it might dry tacky, but I am happy to report that it completely absorbed into my skin without any stickiness.As someone with fair and sensitive skin, I always get nervous incorporating a new product. However, I had no reaction to this whatsoever. It is quite gentle, and my skin has felt soft and hydrated.So the big question is would I purchase this again? I think so. I’m definitely intrigued. The website is pretty convincing, but as always, the proof is in the pudding. While I may see some benefit within a month, or however long this bottle lasts, I really think this is a product that is going to need more time to demonstrate it’s true power of transforming the skin.
Love the texture, not too watery nor too oily, it gets absorbed in my skin very quickly and I love that it doesn’t clog pores! I have sensitive skin and have had bad reactions to other anti aging products before but none with PowerV, which makes it easy to use day and night everyday even around my eyes, without worrying about damaging my skin’s barrier. My skin feels plumped and healthy after using it!
I have always suffered from sensitive skin. Retinol and other harsh actives aren't always ideal. I have always wanted an anti-aging serum that's not harsh. I thought it was impossible to find one(I am there are a few here & there but pretty much all of them are basic & no real anti-aging effects). I was one of the first ones to get early access to The New Skin Care by PowerV.
To be honest, I would have been happy if it just stopped irritating my skin like every other product, but this exceeded my expectations. Redness has gone, fine lines are visibly smoother after just a few weeks, and there's a subtle lifting effect.
I think I accidentally manifested this serum after looking for something like this for years. The most impressive part has been how bright and even-toned my skin looks. WOW, I am a fan for life. I am only a month in - can't wait to see the full results in 6 months.